To respond to climate change and achieve sustainable food production, we need to strengthen resilience to adverse environments. Researchers have been working on crop stress tolerance to evaluate resilience under single stress conditions and to improve its genetics. However, in actual farmland, growth and yield are often limited when crops are grown under multi-stress conditions, a combination of stresses rather than a single stress. Although there is a strong need for research on multi-stress tolerance, it is very challenging for researchers because of the complexity of experimental systems, and it is desirable to solve technical problems such as improving phenotyping techniques and estimating plasticity.