Coinfection with Candida tropicalis and Cytomegalovirus in a Piglet

JARQ : Japan Agricultural Research Quarterly
ISSN 00213551
書誌レコードID(総合目録DB) AA0068709X
Chronic mucocutaneous candidiasis caused by Candida tropicalis was identified in a 43-day-old female piglet with lesions on body surfaces (face, abdomen, limbs, and hooves) and mucosal surfaces of the oral cavity and stomach (nonglandular region). Cytomegalovirus (CMV) inclusion bodies were observed in the epidermis, apocrine sweat gland, rostral plate eccrine gland, buccal gland, duodenal gland, and renal distal tubule. In addition, adenovirus-like inclusion bodies, Cryptosporidium, and Brachyspira were detected in the intestine. The presence of these opportunistic pathogens on or in the skin and oral–gastrointestinal mucosa implies that the piglet had immunological defects, especially in mucocutaneous barriers. Thus, CMV may have facilitated the activity of C. tropicalis and may have contributed to the persistence of candidiasis.
刊行年月日
作成者 Yuuto KAWASHIMA Hiroyasu TAKAHASHI Kiyoko NOBUMOTO Yasuko HANAFUSA Tomoyuki SHIBAHARA Osamu MIKAMI Yoshio KIKU Koichi KADOTA
著者キーワード chronic mucocutaneous candidiasis hereditary immunodeficiency opportunistic infection swine
公開者 Japan International Research Center for Agricultural Sciences
受付日 2021-04-01
受理日 2022-01-26
56
4
言語 eng
備考 In Press