Immunohistochemical Characterization of Five Types of Lymphoid Neoplasms in Calves

JARQ : Japan Agricultural Research Quarterly
ISSN 00213551
書誌レコードID(総合目録DB) AA0068709X
43-03-10.pdf1.85 MB

Five types of lymphoid neoplasms in calves are described. Four cases with clinicopathologic features of the “calf form of lymphoma” were diagnosed as precursor B or T lymphoblastic leukemia. These neoplasms were positive for terminal deoxynucleotidyl transferase (TdT), a marker for immature lymphocytes. The fifth case (thymic B cell lymphoma) was also TdT positive, but was characterized by massive neoplastic involvement of the thymus. The sixth case involved bovine leukemia virus (BLV). As in the majority of previously reported BLV-associated cases, the neoplastic cells expressed CD5, and atypical giant cells were detected. Instead of enzootic bovine leukosis, in which at least two immunophenotypically distinct entities are included, a diagnosis of BLV-associated pleomorphic B-1 B cell lymphoma was made. The last case, involving an epitheliotropic γδ T cell lymphoma, was characterized by epitheliotropism in the gastrointestinal tract and WC1 expression. Since several histologic types of lymphoid neoplasm occur in calves, the term “calf form of lymphoma” should be abandoned for accurate diagnosis.

作成者 KAGAWA Yuuichi TOMITA Keisuke NAKATANI Hidetsugu SATO Kenshi WADA Yoshihiro ISHIKAWA Yoshiharu KADOTA Koichi

bovine leukemia virus



公開者 Japan International Research Center for Agricultural Sciences
国立情報学研究所メタデータ主題語彙集(資源タイプ) Journal Article
開始ページ 239
終了ページ 245
DOI 10.6090/jarq.43.239
権利 Japan International Research Center for Agricultural Sciences
言語 eng