国立研究開発法人 国際農林水産業研究センター | JIRCAS

Luteinizing Hormone Releasing Hormone and Placental Gonadotrophins for Theraphy of Ovarian Quiescence in Cattle

JARQ : Japan Agricultural Research Quarterly
ISSN
00213551
書誌レコードID(総合目録DB)
AA0068709X
本文フルテキスト

This study was conducted to develop an effective theraphy on ovarian quiescence in cattle. In ovarian quiescent cattle, luteinizing hormone releasing hormone analogue (LH-RH-A) induced ovulation indirectly about 36 hr after injection by releasing luteinizing hormone (LH). Human chorionic gonadotrophin (hCG) induced ovulation directly about 36 hr after injection without LH release. Pregnant mare serum gonadotrophin (PMSG) stimulated development, maturation and active estradiol-17β (E2) secretion of follicle(s), so that the actively secreted E2 triggered ovulatory LH surge about 35 hr after injection. Consequently, PMSG induced ovulation about 72 hr after injection. After induced ovulation, hypoplastic and short-lived (Type I) corpus luteum (CL) developed (i.e. induced CL) on LH-RH-A treatment. Type I and well-developed but slightly short-lived (Type II) CL developed on hCG treatment, and Type I, Type II and well-developed and normal life span (Type III) CL did on PMSG treatment. The ovarian cyclic activity started at lower rates on each treatment with LH-RH-A, hCG and PMSG. For initiating the ovarian cyclic activity it was recognized that induced CL was functional enough to increase plasma progesterone level and that a follicle matured with active E2 secretion in accordance with regression of the CL. Therefore, to promote the ovarian cyclic activity PMSG was supplementally dosed at a low level in 6 days after LH-RH-A treatment. The PMSG treatment was expected to stimulate maturation and active E2 secretion of a follicle developing along with regression of the induced CL. This treatment induced the ovarian cyclic activity at a high rate.

刊行年月1991-03-01
作成者Hideo KAMOMAE Yoshihiro KANEDA Ikuo DOMEKI Tatsuo NAKAHARA
データ作成日1991-03-01
国立情報学研究所メタデータ主題語彙集(資源タイプ)Journal Article
24
4
開始ページ306
終了ページ314
言語eng