Immunohistochemical Study of Lymphomas of Abdominal Cavity Origin in Two Cows with Bovine Leukemia Virus
Lymphoid neoplasms of abdominal cavity origin were found in two cows infected with bovine leukemia virus (BLV). Case 1 was a 3-year-old Japanese Black cow affected with a B-1 B cell lymphoma. Case 2 was a 14-year-old Japanese Black cow that developed a γδ T cell lymphoma. Immunohistochemically, CD79a-positive lymphoma cells were observed in case 1, whereas CD3-, WC1- or perforin-positive ones were seen in case 2. Despite the expression of CD5 in both lymphomas, the reactivity was surface or cytoplasmic in case 1 and surface membrane in case 2. Erythrophagia by tumor cells of both cases was considered to be due to the fact that their normal counterparts were more primitive forms than conventional lymphocytes.
|作成者||ABE Yuka SHOJI Hiroshi OTA Kazuhiro TAKAHASHI Masahiro KATSURAGI Kiyohito TAKEDA Yoshie NAKAMURA Kazunori ISHIKAWA Yoshiharu KADOTA Koichi|
B-1 B cell
γδ T cell
|公開者||Japan International Research Center for Agricultural Sciences|
|権利||Japan International Research Center for Agricultural Sciences|