国立研究開発法人 国際農林水産業研究センター | JIRCAS

Enhancement of Interleukin-2 Production in CCRF-CEM, Human T-Cell Leukemia, by Tea Flavonols

JARQ : Japan Agricultural Research Quarterly
ISSN
00213551
書誌レコードID(総合目録DB)
AA0068709X
本文フルテキスト

Human T-cell leukemia, CCRF-CEM, produced interleukin (IL)-2 stimulated with phorbol myristate acetate (PMA) and pokeweed mitogen (PWM). In PMA/PWM stimulation, IL-2 production in CCRF-CEM was increased by treatment with kaempferol or quercetin, tea (Camellia sinensis L.) flavonols. In this study, we concluded that (1) flavonols affected the expression of CCRF-CEM surface molecules, (2) CCRF-CEM was activated by flavonols, achieving a state receptive to stimulation, and (3) IL-2 production and mRNA expression were promoted by flavonols.

刊行年月2005-01-01
作成者ASAI KazumiMORIWAKI SawakoMAEDA-YAMAMOTO Mari
著者キーワード

tea (Camellia sinensis L.)

cytokine

kaempferol

quercetin

myricetin

公開者Japan International Research Center for Agricultural Sciences
データ作成日2005-01-01
国立情報学研究所メタデータ主題語彙集(資源タイプ)Journal Article
39
1
開始ページ51
終了ページ55
DOI10.6090/jarq.39.51
権利Japan International Research Center for Agricultural Sciences
言語eng