Development and Fundamental Characteristics of a Human Gastric Digestion Simulator for Analysis of Food Disintegration

Japan Agricultural Research Quarterly
ISSN 00213551
NII recode ID (NCID) AA0068709X

Gastric digestion is the major digestion process in humans and is strongly affected by both physical and chemical digestion. In vitro approaches using different gastric digestion models have received a great deal of attention in several scientific and industrial fields, including food science and technology, due to experiments being conducted under various conditions and with better reproducibility of the experiment data. The development of simple in vitro gastric digestion devices that enable quantitative consideration of the influence of gastric peristalsis has been necessary for simulating and analyzing the disintegration of solid foods in the stomach. The authors and co-workers recently developed a human gastric digestion simulator (GDS) that simplifies the antrum geometry, is capable of simulated gastric peristalsis, and which enables direct observation of the disintegration of food particles in the gastric contents. This article provides a brief overview of our findings regarding the GDS. First, the concept and development of the GDS is introduced. The disintegration characteristics of representative (model) foods using the GDS are described next, providing insights into the digestion processes influenced by gastric peristalsis. After further improvement, the GDS is expected to offer potential as a tool for designing novel nutraceutical and functional foods for which digestibility is well controlled.

Date of issued
Creator Isao KOBAYASHI Hiroyuki KOZU Zheng WANG Hiroko ISODA Sosaku ICHIKAWA
Subject

Antrum

direct observation

human stomach

in vitro device

peristalsis

Publisher Japan International Research Center for Agricultural Sciences
Available Online
NII resource type vocabulary Journal Article
Volume 51
Issue 1
spage 17
epage 25
DOI 10.6090/jarq.51.17
Rights Japan International Research Center for Agricultural Sciences
Relation : J-STAGE
Language eng

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