Degradation of Wheat Epitope Peptides for Atopic Dermatitis and Exercise-Induced Anaphylaxis by Microbial Proteases
ISSN | 00213551 |
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NII recode ID (NCID) | AA0068709X |
Epitope peptides of wheat gliadins and glutenins for atopic dermatitis, PQQPF and QQQPP, were degraded by the microbial proteases of Streptomyces griseus and Aspergillus oryzae. The proteases of Bacillus licheniformis and Bacillus amyloloiquefasiens degraded wheat gliadins and glutenins, but had little or no effect on the epitopes. A 16-mer peptide of CSQQQQPPFSQQQPPF, which incorporated this glutenin epitope twice, was also hydrolyzed by these proteases, and no peptide containing QQQPP was shown after the reaction with S. griseus protease. The proteases of S. griseus and A. oryzae also degraded epitope peptides of wheat gliadins and glutenins for exercise-induced anaphylaxis, QQIPQQQ, QQFPQQQ and QQPGQ.
Date of issued | |
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Creator | OITA Shigeru |
Subject |
Triticum aestivum allergen enzymatic degradation |
Publisher | Japan International Research Center for Agricultural Sciences |
Available Online | |
NII resource type vocabulary | Journal Article |
Volume | 46 |
Issue | 1 |
spage | 89 |
epage | 93 |
DOI | 10.6090/jarq.46.89 |
Rights | Japan International Research Center for Agricultural Sciences |
Language | eng |