Enhancement of Interleukin-2 Production in CCRF-CEM, Human T-Cell Leukemia, by Tea Flavonols
JARQ : Japan Agricultural Research Quarterly
ISSN | 00213551 |
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書誌レコードID(総合目録DB) | AA0068709X |
本文フルテキスト
39-01-08.pdf215.62 KB
Human T-cell leukemia, CCRF-CEM, produced interleukin (IL)-2 stimulated with phorbol myristate acetate (PMA) and pokeweed mitogen (PWM). In PMA/PWM stimulation, IL-2 production in CCRF-CEM was increased by treatment with kaempferol or quercetin, tea (Camellia sinensis L.) flavonols. In this study, we concluded that (1) flavonols affected the expression of CCRF-CEM surface molecules, (2) CCRF-CEM was activated by flavonols, achieving a state receptive to stimulation, and (3) IL-2 production and mRNA expression were promoted by flavonols.
刊行年月日 | |
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作成者 | ASAI Kazumi MORIWAKI Sawako MAEDA-YAMAMOTO Mari |
著者キーワード |
tea (Camellia sinensis L.) cytokine kaempferol quercetin myricetin |
公開者 | Japan International Research Center for Agricultural Sciences |
オンライン掲載日 | |
国立情報学研究所メタデータ主題語彙集(資源タイプ) | Journal Article |
巻 | 39 |
号 | 1 |
開始ページ | 51 |
終了ページ | 55 |
DOI | 10.6090/jarq.39.51 |
権利 | Japan International Research Center for Agricultural Sciences |
言語 | eng |