Determination of antimutagenic constituents from edible Zingiberaceae plants produced in Thailand
Country
Thailand
Description
[Synopsis]
Fingerroot (Boesenbergia pandurata Schl.) and galanga (Languas galanga), that belong to Zingiberaceae family, are common edible plants in Thailand. Methanolic extracts from fingerroot and galanga showed a potent antimutagenic activity on the mutagenesis induced by 3-amino-1 ,4-dimethyl-5H-pyrido[4,3-b]indole (Trp-P- 1) in Salmonella typhimurium TA98. Then the isolation and characterization of the antimutagenic compounds from both plants was carried out using reversed phase column chromatography. Six active compounds (FR1, FR2, FR3, FR4, FR5 and FR6) from fingerroot and two active compounds (GI and G2) from galanga were isolated. The physico-chemical properties of these coinpounds were deterrnined by liquid chromatography-mass spectrometry and UV-absorption spectrometry. FRI and FR3 were characterized as chalcone derivatives, and. FR2 and FR4 were characterized as flavanone derivatives. FR5 and FR6 could not be characterized due to insufficient information. G I and G2 were estimated to be phenylpropanoid derivatives. The antimutagenic activity of the six isolated compounds from fingerroot was higher than two compounds from galanga, at the concentration of 25 µ g/plate. All the isolated compounds was fairly stable upon the heat treatment and survived after heating at 105 C for 15 min.
- Affiliation
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Japan International Research Center for Agricultural Sciences Crop Production and Postharvest Technology Division
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Kasetsart University
- Classification
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Technical A
- Term of research
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FY1997-1999
- Responsible researcher
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Trakoontivakorn Gassinee ( Kasetsart University )
NAKAHARA Kazuhiko ( Food Science and Technology Division )
- ほか
- Japanese PDF
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1998_10_A3_ja.pdf619.21 KB